Publications
Journal Articles
Webby, Celia J., Jiao, Wanting, Hutton, Richard D., Blackmore, Nicola J., Baker, Heather M., Baker, Edward N., Jameson, Geoffrey B. and Parker, Emily J. (2010). Synergistic allostery: A sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis. Journal of Biological Chemistry, 285 (40), 30567-30576. doi: 10.1074/jbc.M110.111856
Mantri, Monica, Krojer, Tobias, Bagg, Eleanor A., Webby, Celia J., Butler, Danica S., Kochan, Grazyna, Kavanagh, Kathryn L., Oppermann, Udo, McDonough, Michael A. and Schofield, Christopher J. (2010). Crystal structure of the 2-Oxoglutarate- and Fe(II)-dependent lysyl hydroxylase JMJD6. Journal of Molecular Biology, 401 (2), 211-222. doi: 10.1016/j.jmb.2010.05.054
Webby, Celia J., Wolf, Alexander, Gromak, Natalia, Dreger, Mathias, Schmitz, Corinna, Butler, Danica S., Yates III, John R., Delahunty, Claire M., Hahn, Phillip, Lengeling, Andreas, Proudfoot, Nicholas J., Böttger, Angelika and Schofield, Christopher J. (2009). Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing. Science, 325 (5936), 90-93. doi: 10.1126/science.1175865
Gerken, Thomas, Girard, Christophe A., Tung, Yi-Chun Loraine, Webby, Celia J., Saudek, Vladimir, Hewitson, Kirsty S., Yeo, Giles S. H., McDonough, Michael A., Cunliffe, Sharon, McNeill, Luke A., Galvanovskis, Juris, Rorsman, Patrik, Robins, Peter, Prieur, Xavier, Coll, Anthony P., Ma, Marcella, Jovanovic, Zorica, Farooqi, I. Sadaf, Sedgwick, Barbara, Barroso, Ines, Lindahl, Tomas, Ponting, Chris P., Ashcroft, Frances M., O’Rahilly, Stephen and Schofield, Christopher J. (2007). The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science, 318 (5855), 1469-1472. doi: 10.1126/science.1151710
Webby, Celia J., Baker, Heather M., Lott, J. Shaun, Baker, Edward N. and Parker, Emily J. (2005). Structure of the type II 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAH7P) synthase from Mycobacterium tuberculosis reveals a common ancestry for type I and II enzymes. Journal of Molecular Biology, 354 (4), 927-939. doi: 10.1016/j.jmb.2005.09.093
Webby, Celia J., Patchett, Mark L. and Parker, Emily J. (2005). Characterization of a recombinant type II 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Helicobacter pylori.. Biochemical Journal, 390 (1), 223-230. doi: 10.1042/BJ20050259
Webby, Celia J., Lott, J. Shaun, Baker, Heather M., Baker, Edward N. and Parker, Emily J. (2005). Crystallization and preliminary X-ray crystallographic analysis of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Mycobacterium tuberculosis. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 61 (4), 403-406. doi: 10.1107/S1744309105007931